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Furthermore, novel formulations of intra-articular therapeutics, such as glucosinolates and enhanced hyaluronic acid, are being explored for their potential to provide both analgesic and structural benefits ( FIGURE 5 Artificial intelligence (AI) and digital health technologies are increasingly being integrated into OA care

HGH (Human Growth Hormone): Legal status: Prescription required, controlled substance Schedule: Not scheduled but heavily regulated Illegal to possess without prescription Illegal to sell without DEA licensing Penalties: Can include federal charges Why HGH is different: Federal law specifically criminalizes HGH possession and distribution outside legitimate medical use (Anti-Drug Abuse Act of 1988)

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10.1016/s0092-8674(00)81638-4 Cell 154 StojkovicK.WingS